ea0081p583 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022
Luzi Livio
, Greenway Frank
, Miller Sam
, Matejkova Erika
, McLean Barry
, Zmuda Witold
, Bogdanski Pawel
, Arciszewska Malgorzata
, Sjodin Anders
, Salz Judith
, Bochenek-Mularczyk Anna
, Lewy-Alterbaum Lorena
, Butcher Michael
, Paragh Gyorgy
, Davis Yvonne
, Wilding John
, Golub Howard
, Leider Harry
, Zohar Yishai
, Sannino Alessandro
, Calderon Henry
, Heshmati Hassan
Introduction: Methods to predict clinically meaningful weight loss can help tailor treatment for people with overweight or obesity. LIGHT-UP (NCT03058029), is a multicenter, double-blind, randomized, placebo-controlled study over 25 weeks including 254 people with prediabetes or type 2 diabetes (127 each in the Gelesis200 and placebo arms) with a body mass index between 27 and 40 kg/m2, which demonstrated that Gelesis200 offers a compelling new potential approach in...